Best Niacinamide Cream (Vitamin B3 Cream)

Best Niacinamide Cream (Vitamin B3 Cream) Reviews

Niacinamide cream, also known as B3 cream, nicotinamide and nicotine acid (NTA) is an antioxidant with the ability to improve skin’s moisture barrier, minimize irritation and acne symptoms  and stimulate collagen synthesis.

A nicaniamide cream can be used by multiple skin types. Even though some niacinamide products may be marketed as an “anti aging cream” doesn’t meant that it’s just for those who want to fight wrinkles. Those with acne and oily skin may also benefit based on the efficacy of the ingredients. Here’s a look at the best niacinamide creams below.

Olay Regenerist Micro Sculpting Cream

Olay Regenerist Micro Sculpting is our top pick for an effective and affordable niacinamide cream for wrinkles due to its high grade ingredients which include niacinamide, peptides (Pentapteptide-4), and numerous antioxidants.

Pentapeptide-4 is also known as Matrixyl and has been proven to stimulate collagen production at the 2002 World Congress of Dermatology in Paris. Subjects who used Matrixyl noticed  a significant decrease in wrinkle depth and density.

Reviewers noted firmer, smoother and softer skin, fewer lines

With Olay Regenerist Micro Sculpting Cream you’re getting an effective niacinamide cream with proven ingredients at a reasonable price. Reviewers with rosacea also noticed improvements in their condition, most likely because niacinamide has been proven to ease rosacea inflammation.

Olay Regenerist Micro Sculpting Cream Ingredients

Water, Glycerin, Isohexadecane, Niacinamide, Isopropyl Isostearate, Aluminum Starch Octenylsuccinate, Nylon-12, Dimethicone, Tocopheryl Acetate, Panthenol, Sodium Hyaluronate, Palmitoyl Pentapeptide-4, Carnosine, Camellia Sinensis Leaf Extract, Aloe Barbadensis Leaf, Soluble Collagen, Elastin, Allantoin, Stearyl Alcohol, Polyethylene, Cetyl Alcohol, Sodium Acrylates Copolymer, Behenyl Alcohol, Benzyl Alcohol, Caprylic/Capric Triglyceride, Polyacrylamide, Dimethiconol, PEG-100 Stearate, Stearic Acid, Disodium EDTA, Cetearyl Glucoside, Cetearyl Alcohol, Citric Acid, C12-13 Pareth-3, Laureth-7, C13-14 Isoparaffin, Sodium Hydroxide, Ammonium Polyacrylate, Phenoxyethanol, Sorbic Acid, Butylparaben, Ethylparaben, Isobutylparaben, Methylparaben, Propylparaben, Sodium Benzoate, Mica, Tin Oxide, Titanium Dioxide, Fragrance. Vitamin B3 cream, Vitamin E, Pro-Vitamin B5, Amino-Peptide, Green Tea, Aloe Vera.

 Olay Regenerist Micro Sculpting Cream


Nia 24 Skin Strengthening Complex

What makes Nia 24 Skin Strengthening Complex one of the best niacinamide creams is the fact that it also contains peptides and antioxidants; three of the most important ingredients in an anti-aging cream.

Nia 24 Skin Strengthening Complex With Niacinamide

Nia 24 Skin Strengthening Complex is different it that it contains pro-niacin, a trademarked version of niacinamide with a special delivery system for slow and continuous release. Nia 24 Skin Strengthening Complex  contains more skin beneficial ingredients compared to Olay Regenerist including rosemary extract, ceramide, soy extract and sodium hyaluronate.

Additional beneficial ingredients of this niacin cream include evening primrose and wheat germ oils to deliver moisture, a peptide complex to minmize lines, vitamin A to improve skin texture and antioxidants in the from of green tea and rosemary.  Nia 24 is one of the most potent niacinamide creams we’ve reviewed in terms of overall ingredients. Unfortunately it also happens to be one of the most expensive.

Nia 24 Skin Strengthening Complex Ingredients:

Water (Aqua), Hydrogenated Polyisobutene, Myristyl Nicotinate, Cyclopentasiloxane, Olea Europaea (Olive) Fruit Oil, Cyclomethicone, Squalane, Butylene Glycol, Dimethicone, C12-15 Alkyl Benzoate, Glyceryl Stearate SE, Cetyl Alcohol Glycerin, Polyacrylamide, Pyrus Malus (Apple) Fruit Extract, Aloe Barbadensis Leaf Juice, Glycine Soja (Soybean) Seed Extract, Juglans Regia (Walnut) Seed Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Camellia Sinensis (Green Tea) Leaf Extract, Oenothera Biennis (Evening Primrose) Oil, Triticum Vulgare (Wheat) Germ Oil, Carthamus Tinctorius (Safflower) Seed Oil, Pentadecalactone, Methyldihydrojasmonate, Dodecahydro-3a,6,6,9atetramethylnaphtho( 2,1-b)furan, Myristica Fragrans (Nutmeg) Kernel Extract, Maltol, Ceramide 3,Retinyl Palmitate (Vitamin A Palmitate), Sodium Hyaluronate, Ceramide 2, PEG-8, Phospholipids, Tribehenin, PEG-10 Rapeseed Sterol, Palmitoyl Oligopeptide, Dimethicone Crosspolymer-3,BHT, Laureth-7, C13-14 Isoparaffin, Polysorbate 60, Diazolidinyl Urea, Iodopropynyl Butylcarbamate,Methylparaben,Propylparaben

Nia 24 Skin Strengthening Complex


Cerave PM  (Night Time Niacinamide cream)

Fortunately you don’t need to spend tons of money in order to find a vitamin B3 cream. Cerave PM is available in drugstore and highly recommended by dermatologists. This is probably one of the best niacinamide creams you can get for the price. Besides niacinamide it also contains ceramides and hyaluronic acid. Ceramides work to improve skin’s natural moisture retention (source) while hyaluronic acid is excellent for dry and sensitive skin.

Cerave PM

What we really love about Cerave PM is that it comes in a pump bottle because the packaging prevents ingredients from oxygen exposure plus it’s also more hygienic. Cerave PM’s texture is light; it’s not heavy or “cream-like”; however it is very moisturizing. It’s marketed as a night time niacinamide cream but can also be used during the day time with a sunscreen on top.

Cerave PM would is also an excellent choice for those with acne prone and oily skin due to its light texture and niacinamide content. The only thing missing which we’ll think make Cerave PM perfect is antioxidants and peptides which it lacks. Other than that Cerave PM is still one of the best drugstore niacinamide creams you can buy for the price. You get a lot of product for the price (3 fl oz) and at that price it won’t hurt to use it on your hands or anywhere else you need an extra boost of moisture.

Cerave PM Ingredients

Purified water, glycerin, caprylic/capric triglycerides, niacinamide, behentrimonium methosulfate and cetearyl alcohol, ceteareth-20 and cetearyl alcohol, ceramide 3, ceramide 6-11, ceramide 1, phytosphingosine, hyaluronic acid, cholesterol, dimethicone, polyglyceryl-3 diisostearate, potassium phosphate, dipotassium phosphate, sodium lauroyl lactylate, disodium EDTA, methylparaben, propylparaben, carbomer, xanthan gum.

Cerave PM


Cheryl Lee MD TrueLipid TrueTherapy Ceramide + Nicinamide Cream

Cheryl Lee MD TrueLipid TrueTherapy is formulated by a dermatologist and highly recommended for those with eczema (it’s mentioned at the National Eczema Association website). Ingredients include ceramides, licorice root extract and antioxidants. It’s recommended for those with dry & aging skin, rosacea and those with cutaneous lupus.

We love this formulation for it’s ability to treat a large number of skin conditions and the fact that it contains nicanamides, ceramides and antioxidants. However, niacinamide is listed further down in the ingredient list which means that it doesn’t contain as much niacinamide as products which have it listed towards the beginning such as Olay Regenerist Micro Sculpting Cream and Cerave PM (both reviewed above). With that said; this is not a super potent niacinamide cream but it offers a large number of skin strengthening ingredients.

Reviewers noted that this niacin cream left their skin calm, hydrated and healthy.  Cheryl Lee MD TrueLipid TrueTherapy is non-toxic and hypoallergenic.

Cheryl Lee MD TrueLipid TrueTherapy Ingredients:

Water, Caprylic/Capric Triglyceride (Coconut), Petrolatum, Neopentyl Glycol Diheptanoate, Polyglyceryl -10 Pentastearate, Behenyl Alcohol, Sodium Stearoyl Lactylate, Glyceryl Stearate, Glycerin, Isostearyl Isostearate, Cetyl Alcohol, 1,3 Propanediol (from Corn), C10-30 Cholesterol/Lanosterol Esters, Ceramide 3, Phytosphingosine, Euphorbia Cerifera (Candelilla) Wax, Niacinamide, Glycyrrhetinic Acid (Licorice Root), 1,2 -Hexanediol, Caprylyl Glycol, Disodium EDTA, Xanthan Gum, Gluconolactone

Cheryl Lee MD TrueLipid TrueTherapy


How Niacinamide Cream Works

According to a study published in the British Journal of Dermatology in 2000, niacinamide has been proven to increase ceramide and fatty free acids and prevent skin from losing water content.

Niacinamide cream has also been proven to be an effective acne and rosacea treatment due to its inflammatory properties according this clinical study.  Niacinamide has also been proven to decrease discoloration and hyperpigmentation (source). Given these facts niacinamide is a very beneficial ingredient to have in a cream.

Do Not Use A Niacinamide Cream At The Same Time As Vitamin C Serum

We don’t recommend using niacinamide and vitamin c serum at the same time because these two compounds will form a 1.1 complex according to this study and “cancel each other out” so to speak . For best results use a vitamin c serum in the morning (in order to enhance your sunscreen’s effectiveness) and use a niacinamide or b3 cream at night.

Niacinamide Creams Can Be Used For Both Anti-Aging & Acne

Browse more Niacinamide Creams & B3 Cream products below.